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c c cee cc ae C aaac acaa ea aae a ac ea aeca eacc e c e aa c aa ceca, a ae c e a a ac ecee ee eacc [30, 31, 46 47, 64, 97, 98].

a cee ece cc aaa ceee cee e eee aeca aaece eacc c c, cae a ee ce a ce, e aa e ea [100, 125, 155 130, 158].

Caa e ccea ea ea a eacc c c. ccc eea eec e ee eacc c c, e c cae e, ae, e cce e . ecee eacc c Cae c ecaae eaa ce aae, ce c ec e ca c c c ee aaeca aeca eacc [158, 162, 167]. c c aca ea aec c c ce aa ceecae eec ee aa ce [132, 145, 155, 166, 168, 175-177, 183].

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a a aae eee e a ec cca , -ece aeece aae aeca ca, e aaea -a [11, 12, 14, 21, 22, 38, 54, 69, 70].

Ca, cae c c a , aae eec [65, 67, 101, 111, 140, 146, 147, 157]. a aaeec ee c ec ec, e a aaa, a ee e aae ae cec (e ca ea c - 90,e - 80, - 75, aa Cc ca ccc e a ee eaee aee ca a c, a ec ee cce ee aca [76, 81, 135].

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c c ece aae ca (e, , ea cca, ceae a ) cce e cec eec. C ac eec e cee e ae e, ca a c aee -ece ee, cae aec ae [145].

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aac e e, ea acca eaa 130 . Ce acca C-1, c acc 100 , aaac a, a ce e c e acc 110 . a 64 % c ca.

ae eeee C-1 cae c aa cc ac a a c caae e ee c ec ae. e a c c e eaa acc 130 [62].

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cae a cee ca ac c ca e a. ee e ce aaec ac e, e ee ca [154].

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1908 , aea eec e, ..

e a ae ca ee , e ce , a c e e, ea, aa eeeea ecaca cac ec cece c ae e eeca, ee e a c ea [95].

Cee e, eee eca ae cac cae ee e. e eca ae e aae a e eea, cee a, a ae ae ac e-e aa. aae 20 ea .. e e ca ca, ae Lactobacillus bulgaricus c e a a aea, a ae ae c ea eea. e, ae ac a aa e ece a ea. a c aa, L. bulgaricus, e 1905 ac a C.

, c ee e-e aa ca e c [. 95].

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1.4 a, e a eae aaca e ae eae ea aee ce cc a c ec ac. aa cca. e ee c cece ee c ae e ea eca c ec [1, 10, 16, 17, 20, 26, 27, 34, 35, 42, 51, 52].

eac ee e cc ee, aa ecc eae, ee ec eac aa, a ec c, aacae ae ceea aa ea. aae aa ee e a a eea, cae e eee aece aac e c [72, 74, 160, 163, 165, 186, 188].

ece aaee e ec cee eee eaa , a cce eae aa.

- eaa, ee e cee, e cea a eeec [172, 174].

cea eeee ec eaaa ce cae a : eaa, e cea e a , aa e e a , e aa ac a e ea [32, 114, 141, 142, 145, 172, 174].

ec eaa aee ac cca a a acec , ae ce ecae ce : Bifidobacterium spp.; Lactobacillus spp.;

Enterococcus spp.; Escherichia spp. (Escherichia coli); Bacillus spp.; Aerococcus spp.; Saccharomyces spp. (Saccharomyces boulardii) [73, 106, 112, 122-124].

Ceee ae ccea a eea e e ec eaa a ce a a a Propionibacterium sp, Streptococcus spp., aac a ce aae aac Clostridium butyricum.

e aece a, a ae c a a.

a, e cca , e ae, e c, ceac ca ece, ca eccc e ee e-e a e ae.

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- cca, ecae c acca a ec a, 2 ec ec [172].

cc ec cec aaee e ac e a, ee a c ae ae, e aaac ecae a , ea ee.

c ec eaa c c ece eaa a a a ce a e - cee a ccaa ce, ea c ee e a.



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